Combining two-directional synthesis and tandem reactions:† an efficient strategy for the total syntheses of (±)-hippodamine and (±)-epi-hippodamine‡
Martin Rejzek,Robert A. Stockman,David L. Hughes
Organic & Biomolecular Chemistry Pub Date : 11/08/2004 00:00:00 , DOI:10.1039/B413052A
Abstract

Two-directional total stereoselective syntheses of (±)-hippodamine and (±)-epi-hippodamine, utilising a tandem deprotection/intramolecular double Michael addition sequence as the key step, are presented.

Graphical abstract: Combining two-directional synthesis and tandem reactions: an efficient strategy for the total syntheses of (±)-hippodamine and (±)-epi-hippodamine