Development of a novel oxidatively removable and recyclable linker for combinatorial solid phase synthesis
Wen-Ren Li,Nai-Mu Hsu,Hsueh-Hsuan Chou,Sung Tsai Lin and,Yu-Sheng Lin
Chemical Communications Pub Date : 02/23/2000 00:00:00 , DOI:10.1039/A909236F
Abstract

An appropriately derivatized phenanthridine is shown to behave as a novel, reusable linker which is based on a disubstituted amide anchorage and forms an acid group on oxidative cleavage, but tolerates exposure to acidic, basic and reductive reaction conditions.