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Diastereo- and enantioselective reductive amination of cycloaliphatic ketones by preformed chiral palladium complexes†
Armando Cabrera,Pankaj Sharma,F. Javier Pérez-Flores,Luis Velasco,J. Luis Arias,Laura Rubio-Pérez
Catalysis Science & Technology Pub Date : 03/14/2014 00:00:00 , DOI:10.1039/C4CY00058G
Abstract

An efficient preformed chiral palladium catalyzed direct diastereo- and enantioselective reductive amination of un- and substituted cycloaliphatic ketones with primary aryl amines has been developed.

Graphical abstract: Diastereo- and enantioselective reductive amination of cycloaliphatic ketones by preformed chiral palladium complexes
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