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Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents†
Hugo E. Gottlieb,Grazyna Graczyk-Millbrandt,Graham G. A. Inglis,Abraham Nudelman,David Perez,Yanqiu Qian,Leanna E. Shuster,Helen F. Sneddon,Richard J. Upton
Green Chemistry Pub Date : 04/15/2016 00:00:00 , DOI:10.1039/C6GC00446F
Abstract

Residual solvents often appear as nuisance signals in experimental NMR spectra, and many chemists turn to well-known literature sources to quickly identify such peaks. While these publications are very useful, they do not currently include many solvents exemplified in green chemistry-related literature. This work provides a single compiled reference for NMR chemical shifts of 80 solvents in each of 6 deuterated NMR solvents. The overall green chemistry assessments, as reached via the methodology of the GSK Solvent Sustainability Guide, are displayed on these charts.

Graphical abstract: Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents
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