Cu-Catalyzed/mediated synthesis of N-fluoroalkylanilines from arylboronic acids: fluorine effect on the reactivity of fluoroalkylamines†,10.1039/C8OB01581C

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Cu-Catalyzed/mediated synthesis of N-fluoroalkylanilines from arylboronic acids: fluorine effect on the reactivity of fluoroalkylamines†

Hui Wang,Yuan-Hong Tu,De-Yong Liu,Xiang-Guo Hu

Organic & Biomolecular Chemistry Pub Date : 08/03/2018 00:00:00 , DOI:10.1039/C8OB01581C

Abstract

An oxidative coupling reaction of fluoroalkylamines with arylboronic acids has been achieved for the first time. Fluorine has profound influence on the reactivity and fluoroalkylated amines have the following reactivity trend: difluoroethylamine > trifluoroethylamine > pentafluoropropylamine ≈ heptafluorobutylamine.