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Design of a reversible biotin analog and applications in proteinlabeling, detection, and isolation†
Lai-Qiang Ying,Bruce P. Branchaud
Chemical Communications Pub Date : 06/27/2011 00:00:00 , DOI:10.1039/C1CC12738A
Abstract

To expand the applicability of the biotin–(strept)avidin system, a biotin analog with reversible binding under non-denaturing conditions has been designed, and its applications in protein labeling, detection, and isolation have been evaluated.

Graphical abstract: Design of a reversible biotin analog and applications in protein labeling, detection, and isolation
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