An interesting dicarboxyl-pyridyl functionalized difluoroboron dipyrromethene dye probe (2,6-diCO₂H-BODIPY), showing molecular packing in a 3D microporous supramolecular framework with 1D channels, is successfully fabricated and characterized, exhibiting a remarkable dual-responsive fluorescence sensitivity for recognizing both Hg²⁺ and Cu²⁺ ions based on the ion-induced H-aggregation.