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Direct borylation of benzyl alcohol and its analogues in the absence of bases†
Zhi-Chao Cao,Fei-Xian Luo,Wen-Juan Shi
Organic Chemistry Frontiers Pub Date : 09/10/2015 00:00:00 , DOI:10.1039/C5QO00243E
Abstract

Direct borylation of arylmethanols to synthesize important and useful benzylboronates was carried out through Pd(OAc)2-catalyzed sp3 C–O activation. This borylation is compatible with various functional groups under mild conditions in the absence of any bases, offering an atom- and step-economical way to produce benzylboron compounds.

Graphical abstract: Direct borylation of benzyl alcohol and its analogues in the absence of bases
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