Direct construction of 2-alkylbenzo-1,3-azoles via C–H activation of alkanes for C–C and C–X (X = O, S) bond formation†,10.1039/C4OB02488E

批量搜索

批量搜索

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Direct construction of 2-alkylbenzo-1,3-azoles via C–H activation of alkanes for C–C and C–X (X = O, S) bond formation†

Arvind K. Yadav,Lal Dhar S. Yadav

Organic & Biomolecular Chemistry Pub Date : 12/24/2014 00:00:00 , DOI:10.1039/C4OB02488E

Abstract

Copper catalyzed straightforward synthesis of 2-alkylbenzoxa(thia)azoles from aryl isocyanates/isothiocyanates and simple alkanes is reported. The protocol utilizes ditertiary butyl peroxide (DTBP) as a radical initiator and involves sequential formation of C–C and C–X (X = O, S) bonds followed by aromatization in a one-pot procedure.