Diastereoselective γ-vinyl butyrolactone synthesis viagold catalyzed cyclization of allylic acetate†
Ya-Hui Wang,Li-Li Zhu,Yu-Xin Zhang,Zili Chen
Chemical Communications Pub Date : 12/04/2009 00:00:00 , DOI:10.1039/B913348H
Abstract

An efficient method for the preparation of polysubstituted γ-vinyl butyrolactones was developed through gold catalyzed highly diastereoselective cyclization of the malonate substituted allylic acetates.

Graphical abstract: Diastereoselective γ-vinyl butyrolactone synthesis via gold catalyzed cyclization of allylic acetate