DNA minor groove hydration probed with 4’-alkylated thymidines
Ilka Detmer,Daniel Summerer,Andreas Marx
Chemical Communications Pub Date : 09/19/2002 00:00:00 , DOI:10.1039/B207582M
Abstract
Employing modified oligonucleotides that are 4′-alkylated site-specifically we investigated the involvement of DNA minor groove hydration on DNA duplex stability and helix conformation.