An efficient method for the synthesis of asymmetric tripodal ligands from aryl aldehydes and (2-hydro-xybenzyl-2-pyri-dylmethyl)amine was developed. It has the advantages of short reaction times, high yields and a simple methodology. The title ligands were characterized using a combination of ¹H NMR, ¹³C NMR, FT-IR and H RMS spectroscopies. The structures of some of the ligand were confirmed by single-crystal X-ray diffraction.