Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions†,10.1039/C5GC01978H

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Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions†

Yanjun Xie,Jun Wu,Xingzong Che,Ya Chen,Huawen Huang

Green Chemistry Pub Date : 09/10/2015 00:00:00 , DOI:10.1039/C5GC01978H

Abstract

An efficient procedure for pyrido[1,2-a]benzimidazole preparation from 2-aminopyridines and cyclohexanones under metal-free conditions is described. Non-aromatic cyclohexanones were used as the aryl source via a dehydrogenation–aromatization process using molecular oxygen as the green oxidant.