We report the entrapment of perylene dianhydride molecules into MOF5 pores with strong interaction between host and guest, and with a remarkable electroluminescence response. Optical microscopy, SEM, PXRD and fluorescence spectra clearly show the stabilization of isolated PDA molecules inside the MOF5 pore structure, after careful host activation. Laser flash photolysis reveals a strong interaction between perylene dianhydride molecules and MOF5 through changes in the charge separation state characteristic of MOF5. A electroluminescence cell was prepared using PDA@MOF5 as active material, with a remarkable electroluminescence response.