DNA oxidation by peroxo-chromium(v) species: oxidation of guanosine to guanidinohydantoin
Lamis Joudah,Shadi Moghaddas,Rathindra N. Bose
Chemical Communications Pub Date : 07/11/2002 00:00:00 , DOI:10.1039/B205407H
Abstract
Reactions of peroxo-chromium(V) complexes with DNA afforded mainly guanine oxidation yielding, a four-electron oxidation product, guanidinohydantoin, and exhibited extensive base labile strand scission.
