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Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy†
Jiabao Zhuang,Hanxiao Yang,Yue Li,Bing Wang,Nan Li,Na Zhao
Chemical Communications Pub Date : 01/28/2020 00:00:00 , DOI:10.1039/D0CC00394H
Abstract

Two efficient photosensitizers (PSs) with aggregation-induced emission characteristics were designed and synthesized for specific lysosome-targeted photodynamic therapy (PDT). Both PSs efficiently discriminated Gram-positive bacteria from Gram-negative bacteria and killed Gram-positive bacteria through the PDT effect.

Graphical abstract: Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy
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