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Design of N-cinnamyl sulfinamides as new sulfur-containing olefinligands for asymmetric catalysis: achieving structural simplicity with a categorical linear framework†
Shen-Shuang Jin,Hui Wang,Ting-Shun Zhu,Ming-Hua Xu
Organic & Biomolecular Chemistry Pub Date : 11/30/2011 00:00:00 , DOI:10.1039/C2OB06723D
Abstract

The design and development of an extraordinarily interesting new class of chiral sulfur–olefin hybrid ligands with remarkable structural simplicity were described. These unique sulfinamide–olefin ligands have been proved to be highly effective ligands in rhodium-catalyzed asymmetric 1,4-addition reactions of aryl boronic acids to α,β-unsaturated carbonyl compounds (up to 99% yield and 98% ee).

Graphical abstract: Design of N-cinnamyl sulfinamides as new sulfur-containing olefin ligands for asymmetric catalysis: achieving structural simplicity with a categorical linear framework
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