Enantioselective conjugate addition of thiols to enones
and enals catalyzed by chiral N-oxide–cadmium complex
Makoto Saito,Makoto Nakajima,Shunichi Hashimoto
Chemical Communications Pub Date : 09/14/2000 00:00:00 , DOI:10.1039/B005994N
Abstract
A novel method of enantioselective conjugate addition of thiols to enones and enals produces sulfides with enantioselectivities up to 78% ee, employing a cadmium complex of (S)-3,3′-dimethyl-2,2′-biquinoline N,N′-dioxide 1 as a catalyst.
