Enzymatic activation of a matrix metalloproteinase inhibitor†
Jody L. Major Jourden,Seth M. Cohen
Chemical Communications Pub Date : 01/18/2010 00:00:00 , DOI:10.1039/B923302D
Abstract
Matrix metalloproteinase inhibitors (MMPi) possessing a glucoseprotecting group on the zinc-binding group (ZBG) show a dramatic increase in inhibitory activity upon cleavage by β-glucosidase.
