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Efficient pseudo-five-component coupling-Fiesselmann synthesis of luminescent oligothiophenes and their modification†‡
Marco Teiber,Sönke Giebeler,Timo Lessing,Thomas J. J. Müller
Organic & Biomolecular Chemistry Pub Date : 03/20/2013 00:00:00 , DOI:10.1039/C3OB40124C
Abstract

(Hetero)aryl bis-acid chlorides and terminal alkynes, or likewise acid chlorides and terminal dialkynes, and ethyl 2-mercaptoacetate can be reacted to give highly luminescent symmetrical terthiophenes and quinquethiophenes in the sense of a consecutive pseudo-five-component reaction in good to excellent yields. Further functionalization of the obtained oligomers can be readily achieved by halogenation followed by a metal-catalyzed coupling reaction to give α,ω-diester substrates for subsequent transformations into highly functionalized materials.

Graphical abstract: Efficient pseudo-five-component coupling-Fiesselmann synthesis of luminescent oligothiophenes and their modification
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