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Enantioselective vinylogous Michael addition of β,γ-unsaturated butenolide to 2-iminochromenes†
Vijay Gupta,Ravi P. Singh
New Journal of Chemistry Pub Date : 06/04/2019 00:00:00 , DOI:10.1039/C9NJ01584A
Abstract

An efficient organocatalyzed asymmetric synthesis of 2-amino-4-(2-furanone)-4H-chromene-3-carbonitriles via vinylogous Michael addition of non-activated β,γ-unsaturated butenolide to 2-iminochromenes has been realized.

Graphical abstract: Enantioselective vinylogous Michael addition of β,γ-unsaturated butenolide to 2-iminochromenes
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