Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing†,10.1039/C4CC09905B

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing†

Ming Wang,Guanxin Zhang,Deqing Zhang

Chemical Communications Pub Date : 01/27/2015 00:00:00 , DOI:10.1039/C4CC09905B

Abstract

DNA nanodevices capable of “NOR” and “NAND” logic operations were developed using enzymatic reactions to generate an acidic pH gradient and drive the conformation change of cytosine-rich DNA. Due to the high selectivity and sensitivity of the enzymatic reactions in driving DNA logic gates, novel fluorescent biosensors were further designed for enzyme activity assay and glucose sensing.