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FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues†
Xiangqing Chang,Xiongfei Zhang,Zhiwei Chen
Organic & Biomolecular Chemistry Pub Date : 05/18/2018 00:00:00 , DOI:10.1039/C8OB00942B
Abstract

An intriguing conversion of arylglyoxal, cyclic dicarbonyl compounds and phenols to diverse furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic protocol, a variety of furan analogues could be easily obtained in moderate to good yields with different substituted patterns by varying the reaction medium. Atom-economical characteristics and mild conditions of this method are in accord with the concept of modern green chemistry.

Graphical abstract: FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues
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