Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants†
Jian Zhang,Hefang Shi,Yuyong Ma,Biao Yu
Chemical Communications Pub Date : 07/06/2012 00:00:00 , DOI:10.1039/C2CC34404A
Abstract
Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.