Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay†
Richard C. Knighton,Mark R. Sambrook,Jack C. Vincent,Simon A. Smith,Christopher J. Serpell,James Cookson,Matthew S. Vickers,Paul D. Beer
Abstract
The dansyl fluorophore ligated to gold nanoparticles via imidazole and amine groups affords conjugates capable of detecting micromolar concentrations of the chemical warfare agent sulfur mustard by a fluorescence switching ‘ON’ displacement assay.