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Embedding magnetic nanoparticles into coordination polymers to mimic zinc ion transporters for targeted tumor therapy†
Zhaowei Chen,Kai Dong,Zhen Liu,Fang Pu,Jinsong Ren,Xiaogang Qu
Chemical Communications Pub Date : 09/27/2016 00:00:00 , DOI:10.1039/C6CC06467A
Abstract

Magnetic nanoparticle-embedded coordination polymers could act as mimics for zinc ion transporters for targeted cancer therapy. Compared with traditional zinc ionophores, our system could realize targeted and internal environment responsive transport of zinc ions to suppress the tumour growth while minimizing nonspecific injury to normal tissues.

Graphical abstract: Embedding magnetic nanoparticles into coordination polymers to mimic zinc ion transporters for targeted tumor therapy
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