A multi-component synthesis of N-substituted 2-amino-3-cyano pyrroles via ring-opening of nitroepoxides†,10.1039/C7NJ04584K

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A multi-component synthesis of N-substituted 2-amino-3-cyano pyrroles via ring-opening of nitroepoxides†

Xingyu Liu,Zhuang Nie,Jiaan Shao,Wenteng Chen,Yongping Yu

New Journal of Chemistry Pub Date : 01/12/2018 00:00:00 , DOI:10.1039/C7NJ04584K

Abstract

A multi-component synthesis of N-substituted 2-amino-3-cyano pyrroles from nitroepoxides, amines and malononitrile has been demonstrated. The reaction proceeded well for a wide range of nitroepoxides and amines under mild conditions without transition metal catalysis via the formation of three new bonds.