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Enhanced translocation of poly(dt)45 through an α-hemolysin nanopore by binding with antibody†
Yi-Lun Ying,Da-Wei Li,Yang Li,Jeremy S. Lee,Yi-Tao Long
Chemical Communications Pub Date : 04/14/2011 00:00:00 , DOI:10.1039/C0CC05787H
Abstract

The translocation time of poly(dT)45 through an α-hemolysin pore was reduced in the presence of a DNA-binding Fab fragment. The Fab acts as a rudder to steer the DNA into the pore.

Graphical abstract: Enhanced translocation of poly(dt)45 through an α-hemolysin nanopore by binding with antibody
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