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Gold-catalyzed intermolecular reaction of 2-(1-alkynyl)-2-alken-1-ones with diarylethenes to construct polysubstituted cyclopenta[c]furans through a cascade heterocyclization/[3+2] cycloaddition sequence†
Ting He,Pin Gao,Yi-Feng Qiu,Xiao-Biao Yan,Xue-Yuan Liu,Yong-Min Liang
RSC Advances Pub Date : 09/05/2013 00:00:00 , DOI:10.1039/C3RA44467H
Abstract

A method for preparing polysubstituted cyclopenta[c]furans from 2-(1-alkynyl)-2-alken-1-ones and diarylethenes via gold catalysis is reported. The reaction shows good regioselectivity to afford the desired product in moderate to excellent yields.

Graphical abstract: Gold-catalyzed intermolecular reaction of 2-(1-alkynyl)-2-alken-1-ones with diarylethenes to construct polysubstituted cyclopenta[c]furans through a cascade heterocyclization/[3+2] cycloaddition sequence
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