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Fluorescent nanoparticle sensors with tailor-made recognition units and proximate fluorescent reporter groups†
Xiaoyu Xing,Yan Zhao
New Journal of Chemistry Pub Date : 05/03/2018 00:00:00 , DOI:10.1039/C8NJ01139G
Abstract

The molecular recognition unit of a fluorescent sensor is its most cumbersome part to design and synthesize, but is key to the specificity of the sensor. Molecular imprinting within cross-linked micelles using easily synthesized modular templates allowed us to create analyte-specific binding sites with a nearby fluorescent probe. This strategy makes it straightforward to vary the recognition unit independent of the reporting unit, making the sensor potentially applicable to a wide range of molecular analytes.

Graphical abstract: Fluorescent nanoparticle sensors with tailor-made recognition units and proximate fluorescent reporter groups
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