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Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674†
Sheng Huang,Long Ma,Ming Him Tong,Yi Yu,David O'Hagan
Organic & Biomolecular Chemistry Pub Date : 05/30/2014 00:00:00 , DOI:10.1039/C4OB00970C
Abstract

Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.

Graphical abstract: Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674
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