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A molecular rotor for measuring viscosity in plasma membranes of live cells†
Ismael López-Duarte,Thanh Truc Vu,M. Angeles Izquierdo,James A. Bull,Marina K. Kuimova
Chemical Communications Pub Date : 11/07/2013 00:00:00 , DOI:10.1039/C3CC47530A
Abstract

Molecular rotors have emerged as versatile probes for microscopic viscosity in live cells, however, the exclusive localisation of rotors in the plasma membrane has remained elusive. We report the synthesis, spectroscopic characterisation and live cell imaging of a new BODIPY-based molecular rotor suitable for mapping viscosity in the cell plasma membrane.

Graphical abstract: A molecular rotor for measuring viscosity in plasma membranes of live cells
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