找化学品上960化工网！
《“清朗网络空间 共筑禁毒防线”全国化工行业净网倡议》 全球贸易
平台外贸 广告
化学产品
化学产品
生物产品
功能化工材料
企业名录
Lactoyl-CoA 全氟丁基戊烷 白叶藤碱 全氟己基辛烷 新白叶藤碱 壳寡糖 特色专题-生物多肽
批量搜索 结构搜索 我要询单
  1. 960化工网
  2. 文献
  3. 论文详情
H2-driven biotransformation of n-octane to 1-octanol by a recombinant Pseudomonas putida strain co-synthesizing an O2-tolerant hydrogenase and a P450 monooxygenase†
Lars Lauterbach,Sumire Honda Malca,Bettina M. Nestl,Bernhard Hauer,Oliver Lenz
Chemical Communications Pub Date : 09/11/2015 00:00:00 , DOI:10.1039/C5CC06078H
Abstract

An in vivo biotransformation system is presented that affords the hydroxylation of n-octane to 1-octanol on the basis of NADH-dependent CYP153A monooxygenase and NAD+-reducing hydrogenase heterologously synthesized in a bacterial host. The hydrogenase sustains H2-driven NADH cofactor regeneration even in the presence of O2, the co-substrate of monooxygenase.

Graphical abstract: H2-driven biotransformation of n-octane to 1-octanol by a recombinant Pseudomonas putida strain co-synthesizing an O2-tolerant hydrogenase and a P450 monooxygenase
点击分享 查看原文 点击收藏
推荐化合物
推荐文献