Facile, solvent and ligand free iron catalyzed direct functionalization of N-protected tetrahydroisoquinolines and isochroman†
Michael Ghobrial,Karin Harhammer,Marko D. Mihovilovic,Michael Schnürch
Chemical Communications Pub Date : 10/22/2010 00:00:00 , DOI:10.1039/C0CC02491K
Abstract
An efficient method for an iron catalyzed oxidative indolation and methoxyphenylation of N-protected tetrahydroisoquinolines and isochroman is described including subsequent facile deprotection.