Highly diastereoselective synthesis of anti-γ-N-benzylamino-β-hydroxyphosphonates
Mario Ordóñez,Ricardo de la Cruz-Cordero,Citlali Quiñónes,Angelina González-Morales
Chemical Communications Pub Date : 02/10/2004 00:00:00 , DOI:10.1039/B316262A
Abstract
The reduction of γ-N-benzylamino-β-ketophosphonates 7 derived from readily available amino acids can be carried out stereoselectively with Zn(BH4)2 at −78 °C to produce the anti-γ-amino-β-hydroxyphosphonates 8.
