Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation†
Li Cui,Longwu Ye,Liming Zhang
Chemical Communications Pub Date : 03/30/2010 00:00:00 , DOI:10.1039/C001314E
Abstract
A surprisingly efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities.
![Graphical abstract: Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation](http://hg.y866.cn/compound/lib/scimg/usr/1/C001314E.jpg)
