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A new practical synthesis of triaryl and trisindolylmethanes under solvent-free reaction conditions†
Margherita Barbero,Silvano Cadamuro,Stefano Dughera,Claudio Magistris,Paolo Venturello
Organic & Biomolecular Chemistry Pub Date : 09/06/2011 00:00:00 , DOI:10.1039/C1OB06280H
Abstract

An efficient and practical synthesis of triaryl and trisindolylmethanes is reported via the bisarylation of aryl aldehydes with activated arenes. The new method features mild solvent-free reaction conditions, in most cases nearly stoichiometric reagent ratios, catalytic amount of the readily available, easily-handled, recoverable and reusable Brønsted acid catalyst o-benzenedisulfonimide.

Graphical abstract: A new practical synthesis of triaryl and trisindolylmethanes under solvent-free reaction conditions
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