We present a novel methodology to create in a simple, fast and cheap way an interpenetrating polymer network biomaterial, mixing 2-hydroxyethil methacrylate and poly(dimethylsiloxane), for long-lasting highly hydrophilic microfluidic device prototyping. The presented polymer could be potentially useful to develop point-of-care microfluidic diagnostic devices allowing blood displacement without exertion in microchannels while proving to have low biological analytes adhesion.