Integration of DNA bio-gates and duplex-specific nuclease signal amplification: towards electrochemiluminescence detection of survivin mRNA†
Xiang-Ling Li,Jia-Dong Zhang,Nan Hao,Jing-Juan Xu,Hong-Yuan Chen
Chemical Communications Pub Date : 06/09/2015 00:00:00 , DOI:10.1039/C5CC03693C
Abstract

Using the DNA bio-gate and duplex-specific nuclease assisted target recycling, a facile electrochemiluminescence assay was developed for the sensitive detection of survivin mRNA.

Graphical abstract: Integration of DNA bio-gates and duplex-specific nuclease signal amplification: towards electrochemiluminescence detection of survivin mRNA