A new tetraphenylethylene based AIE sensor with light-up and tunable measuring range for adenosine triphosphate in aqueous solution and in living cells†,10.1039/C7AN01336A

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A new tetraphenylethylene based AIE sensor with light-up and tunable measuring range for adenosine triphosphate in aqueous solution and in living cells†

Guoyu Jiang,Wenping Zhu,Qingqing Chen,Aiping Shi,Yongquan Wu,Guanxin Zhang,Xun Li,Yongdong Li,Xiaolin Fan,Jianguo Wang

Analyst Pub Date : 10/26/2017 00:00:00 , DOI:10.1039/C7AN01336A

Abstract

An AIE based tetraphenylethylene derivative (TPPTPE) was synthesized for light-up sensing of ATP in aqueous solution. The measuring range for ATP can be tuned by varying the concentration of the TPPTPE. A one-step straightforward quantitative analysis of the ATP level in cell lysates can be realized using the TPPTPE. Moreover, the TPPTPE can be used for monitoring apyrase activity in aqueous solution and detecting ATP both in living cancer cell lines and in living normal cell lines.