960化工网
I2/TBPB mediated oxidative reaction of aryl acetaldehydes with amidines: synthesis of 1,2,5-triaryl-1H-imidazoles†
Jing Wang,Fang-Dong Zhang,Dong Tang,Ping Wu,Xue-Guo Zhang,Bao-Hua Chen
RSC Advances Pub Date : 05/09/2017 00:00:00 , DOI:10.1039/C7RA01966A
Abstract

A direct method for the synthesis of 1,2,5-triaryl-1H-imidazoles was achieved easily from cyclization of aryl acetaldehydes with amidines catalyzed by I2. Various substitued groups can be employed, and this reaction proceeds smoothly in moderate to good yields.

Graphical abstract: I2/TBPB mediated oxidative reaction of aryl acetaldehydes with amidines: synthesis of 1,2,5-triaryl-1H-imidazoles
平台客服
平台客服
平台在线客服