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Improved chemoselective, ecofriendly conditions for the conversion of primary alkyl halides into nitroalkanes under PEG400
Roberto Ballini,Luciano Barboni,Alessandro Palmieri
Green Chemistry Pub Date : 08/11/2008 00:00:00 , DOI:10.1039/B805985C
Abstract

Treatment of primary alkyl bromides or iodides with 1.5–3 equivalents of sodium nitrite, at room temperature, in PEG400 as solvent, allows the chemoselective formation of primary nitroalkanes in satisfactory to good yields, under ecofriendly reaction conditions.

Graphical abstract: Improved chemoselective, ecofriendly conditions for the conversion of primary alkyl halides into nitroalkanes under PEG400
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