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Improving success rate of hydrogen-bond driven synthesis of co-crystals†
Christer B. Aakeröy,John Desper,Meg E. Fasulo
CrystEngComm Pub Date : 07/19/2006 00:00:00 , DOI:10.1039/B609709J
Abstract

Increasing the negative charge of a hydrogen-bond acceptor using electron-donating substituents offers a significant improvement in hydrogen-bond driven synthesis of carboxylic acid⋯N-heterocycle co-crystals.

Graphical abstract: Improving success rate of hydrogen-bond driven synthesis of co-crystals
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