In situ, real-time tracking of cell wall topography and nanomechanics of antimycobacterial drugs treated Mycobacterium JLS using atomic force microscopy†
Yangzhe Wu,Anhong Zhou
Chemical Communications Pub Date : 10/09/2009 00:00:00 , DOI:10.1039/B914605A
Abstract
Two antimycobacterial drugsethambutol (EMB) and isoniazid (INH) were found to result in decreases of biomechanical properties including adhesion force, cell wall spring constant, and Young’s modulus in Mycobacterium sp. strain JLS (M. JLS).