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Lewis acid catalyzed Nazarov type cyclization for the synthesis of a substituted indane framework: total synthesis of (±)-mutisianthol†
Dattatraya H. Dethe,Raghavender Boda,Ganesh M. Murhade
Organic Chemistry Frontiers Pub Date : 02/11/2015 00:00:00 , DOI:10.1039/C5QO00005J
Abstract

A new synthetic route has been developed for the synthesis of a substituted indane derivative using Lewis acid catalyzed modified Nazarov type cyclization, which was further applied in the total synthesis of mutisianthol and epi-mutisianthol in a nine step longest linear sequence.

Graphical abstract: Lewis acid catalyzed Nazarov type cyclization for the synthesis of a substituted indane framework: total synthesis of (±)-mutisianthol
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