Ligand influence in the selective gold-mediated synthesis of allenes†
Pierrick Nun,Sylvain Gaillard,Alexandra M. Z. Slawin,Steven P. Nolan
Chemical Communications Pub Date : 10/28/2010 00:00:00 , DOI:10.1039/C0CC03071F
Abstract

The use of [(IPr)AuOH] permits the generation of gold(I)–amine complexes by a silver-free protocol. These in situ or well-defined complexes are used in a straightforward synthetic route to substituted allenes from propargylic acetates. The catalytic activity can be modulated as a function of the nature of the ligand bound to the gold–NHC moiety.

Graphical abstract: Ligand influence in the selective gold-mediated synthesis of allenes