Highly selective dual sensing of ATP and ADP using fluorescent ribonucleopeptide sensors†,10.1039/C8CC09934K

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Highly selective dual sensing of ATP and ADP using fluorescent ribonucleopeptide sensors†

Shun Nakano,Musashi Shimizu,Huyen Dinh,Takashi Morii

Chemical Communications Pub Date : 01/04/2019 00:00:00 , DOI:10.1039/C8CC09934K

Abstract

Highly selective fluorescent sensors for ATP and ADP were constructed from RNA aptamers by applying a modular design of a ribonucleopeptide scaffold. These sensors allow facile and quantitative detection of ATP and ADP simultaneously in a solution and enable monitoring of the time-course changes of ATP and ADP concentrations in an enzymatic reaction.