Iron-catalyzed synthesis of glycine derivativesviacarbon–nitrogen bond cleavage using diazoacetate†
Yoichiro Kuninobu,Mitsumi Nishi,Kazuhiko Takai
Chemical Communications Pub Date : 10/21/2010 00:00:00 , DOI:10.1039/C0CC03781H
Abstract
Treatment of tertiary amines with diazoacetate in the presence of a catalytic amount of an iron salt, FeCl3, in ethanol gave glycine derivatives. In this reaction, a carbon–nitrogen single bond of the amine was cleaved.
