Mn(ii)/O2-promoted oxidative annulation of vinyl isocyanides with boronic acids: synthesis of multi-substituted isoquinolines†
Hao Wang,Yang Yu,Xiaohu Hong
Chemical Communications Pub Date : 09/10/2014 00:00:00 , DOI:10.1039/C4CC06427E
Abstract

An efficient manganese(II)/O2-promoted oxidative radical cascade reaction was developed for the modular synthesis of multi-substituted isoquinolines from easily accessible vinyl isocyanides and boronic acids.

Graphical abstract: Mn(ii)/O2-promoted oxidative annulation of vinyl isocyanides with boronic acids: synthesis of multi-substituted isoquinolines