Environmentally benign L-tyrosine loaded nanoparticles are fabricated and characterized by PCS, TEM, FT-IR and AFM studies. A novel straightforward green approach was applied for the synthesis of dicoumarols and Hantzsch 1,4-dihydropyridines using this catalyst. The structures and purity of these compounds were confirmed by FT-IR and NMR (¹H, ¹³C and DEPT). The flexible and swelling properties of the polymer coating increase L-tyrosine dispersion and its high catalytic activity in organic reactions.